Importing data, “Nore137″, “SampleClass”, and “Gland” below will need to be altered to reflect your column names.
library(“ggplot2″) # Have column names as text, otherwise prepend X mydata = read.table(“mydata.txt”, header=T, stringsAsFactors=F) title = “Norepinephrine Levels in KO vs WT Mouse Brain”
Handles the removal of many elements and adjusts […]
Benchfly catalogs user generated videos focused on lab technique and tips. The site provides insight into many aspects of science which you probably have never considered. Fun.
To educate and empower scientists in and out of the lab, enabling their next big breakthroughs – faster.
http://www.benchfly.com/about.php
http://www.idtdna.com/scitools/scitools.aspx
A collection of useful tools including: Oligo Analyzer, to determine the stability and folding motifs of oligos; PrimerQuest, a primer design tool; and many other nucleic acid technique design tools.
Mfold
http://mfold.rna.albany.edu/?q=mfold
Addressing an analogous problem to protein folding, mfold uses computer algorithms to predict the secondary structure of single stranded RNA.
http://www.ncbi.nlm.nih.gov/sites/genome
The genome page of the NCBI is an excellent place for exploration. The page links to browse-able genomes, taxonomy information as well as the BLAST tools.
Pfam
Pfam is a collection of multiple sequence alignments and profile hidden Markov models (HMMs). Each Pfam HMM represents a protein family or domain. By searching a protein sequence against the Pfam library of HMMs, you can determine which domains it carries i.e. its domain architecture. Pfam can also be used to analyse proteomes […]
http://www.ncbi.nlm.nih.gov/Structure/VAST/vast.shtml
VAST works to find structurally similar, folded protein structures within its database.
http://crystals.otterbein.edu/
Crystallographic Resources at Otterbein University offers a great resource for visualizing packing structures and crystallographic point groups. Great for those learning about crystallography.
http://symmetry.otterbein.edu/
The Symmetry Resources at Otterbein University website offers great visualizations of different point groups. The site is targeted at those learning about symmetry and also includes a few conceptual tutorials.
http://blast.ncbi.nlm.nih.gov/
BLAST compares a sequence of DNA or amino acids to a massive database and returns information about how similar the sequences are.
The comparison of nucleotide or protein sequences from the same or different organisms is a very powerful tool in molecular biology. By finding similarities between sequences, scientists can infer the function […]
http://scop.mrc-lmb.cam.ac.uk/scop/
SCOP is a hierarchical classification of proteins. Top in the classification are large fold types and digging down leads to small group of similar proteins.
The site’s classification also produces some interesting statistics on the fold types of proteins which can be found on the site.
http://www.cathdb.info/
CATH is a protein structure classification database. The database is organized by Class, Architecture, Topology, and Homologous super-family.
For any given structure classified in the database, CATH gives you information on the structure and function of that protein. The evolutionary relationships involving the structure of interest and other proteins in the database can also […]
The Protein Data Bank (PDB) operated by the Research Collaboratory for Structural Bioinformatics (RCSB) is a premier catalog of large crystal models and NMR models of proteins. The database also includes methods for searching by nucleic acids and ligands.
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